Senegal goalkeepeer Edouard Mendy and Kalidou Koulibaly have tested positive for Covid-19.
The two Senegal top players will miss their AFCON opener against Zimbabwe on Monday, January 10.
Mendy was in the post last week for Chelsea against Liverpool in the English Premiership which ended 2-2.
Report from other reliable sources claims five Burkina Faso players will miss the AFCON opening game against Cameroon after testing positive for the virus.
